Bu/MTX TDM Kit - Transplant Applications

Busulfan AUC calibration prevents sinusoidal obstruction syndrome (target 900-1400µM×min Day -9 to -6).

Hematology labs measure MTX Day 4 (<0.2µM) preventing leucovorin rescue delay.

Stable isotope standards compensate matrix effects maintaining ±15% accuracy.

Prevents graft failure (Bu underdose) and mucositis (MTX overdose).