Jaffe Creatinine End-Point - Routine Applications

Alkaline picrate reaction (510nm) quantifies 0.2-20 mg/dL across CKD-EPI equation and cisplatin nephrotoxicity monitoring workflows.

Clinical laboratories achieve ±0.3 mg/dL accuracy preventing MDRD misclassification. Ascorbate oxidase eliminates vitamin C interference.

Quality control confirms kinetic discrimination, end-point stability, and 18-month shelf life. Isotonic diluent prevents pseudohyponatremia artifacts.